HNF1B Antibody
| Code | Size | Price |
|---|
| PSI-55-640-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
Hepatocyte nuclear factor 1-beta, HNF-1-beta, HNF-1B, Homeoprotein LFB3, Transcription factor 2, TCF-2, Variant hepatic nuclear factor 1, vHNF1, HNF1B, TCF2
Application Note:
For WB starting dilution is: 1:1000
Background:
This gene encodes a member of the homeodomain-containing
superfamily of transcription factors. The protein binds to DNA as
either a homodimer, or a heterodimer with the related protein
hepatocyte nuclear factor 1-alpha. The gene has been shown to
function in nephron development, and regulates development of the
embryonic pancreas. Mutations in this gene result in renal cysts
and diabetes syndrome and noninsulin-dependent diabetes mellitus,
and expression of this gene is altered in some types of cancer.
Multiple transcript variants encoding different isoforms have been
found for this gene.
Background References:
- Jablonski, K.A., et al. Diabetes 59(10):2672-2681(2010)
- Oram, R.A., et al. Am. J. Obstet. Gynecol. 203 (4), 364 (2010) :
- Takata, R., et al. Nat. Genet. 42(9):751-754(2010)
- Liu, H., et al. Prostate (2010) In press :
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Predicted species reactivity based on immunogen sequence: Mouse, Rat
Immunogen:
This HNF1B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 498-529 amino acids from the C-terminal region of human HNF1B.
NCBI Gene ID #:
6928
NCBI Official Name:
Hepatocyte nuclear factor 1-beta
NCBI Official Symbol:
HNF1B
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
61 kDa
Protein Accession #:
P35680
Protein GI Number:
547664
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Obesity
Swissprot #:
P35680
User NOte:
Optimal dilutions for each application to be determined by the researcher.