LETM1 Antibody

ProSci
Product Code: PSI-59-207
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-59-207-400ul400ul£626.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Images

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Western blot analysis in 293 cell line lysates (35ug/lane).

Western blot analysis in 293 cell line lysates (35ug/lane).

Further Information

Additional Names:
LETM1 and EF-hand domain-containing protein 1, mitochondrial, Leucine zipper-EF-hand-containing transmembrane protein 1, LETM1
Application Note:
For WB starting dilution is: 1:1000
Background:
This gene encodes a protein that is localized to the inner mitochondrial membrane. The protein functions to maintain the mitochondrial tubular shapes and is required for normal mitochondrial morphology and cellular viability. Mutations in this gene cause Wolf-Hirschhorn syndrome, a complex malformation syndrome caused by the deletion of parts of the distal short arm of chromosome 4. Related pseudogenes have been identified on chromosomes 8, 15 and 19.
Background References:
  • Jiang, D., et al. Science 326(5949):144-147(2009)
  • Piao, L., et al. Cell. Signal. 21(5):767-777(2009)
  • Piao, L., et al. Cancer Res. 69(8):3397-3404(2009)
  • Tamai, S., et al. J. Cell. Sci. 121 (PT 15), 2588-2600 (2008) :
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This LETM1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 577-607 amino acids from the C-terminal region of human LETM1.
NCBI Gene ID #:
3954
NCBI Official Name:
LETM1 and EF-hand domain-containing protein 1, mitochondrial
NCBI Official Symbol:
LETM1
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
83 kDa
Protein Accession #:
O95202
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Obesity
Swissprot #:
O95202
User NOte:
Optimal dilutions for each application to be determined by the researcher.