MRPL19 Antibody

ProSci
Product Code: PSI-60-446
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-60-446-400ul400ul£626.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Images

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Western blot analysis in Ramos cell line lysates (35ug/lane).

Western blot analysis in Ramos cell line lysates (35ug/lane).

Further Information

Additional Names:
39S ribosomal protein L19, mitochondrial, L19mt, MRP-L19, 39S ribosomal protein L15, mitochondrial, L15mt, MRP-L15, MRPL19, KIAA0104, MRPL15
Application Note:
For WB starting dilution is: 1:1000
Background:
Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein. [provided by RefSeq].
Background References:
  • Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :
  • Anthoni, H., et al. Hum. Mol. Genet. 16(6):667-677(2007)
  • Hillier, L.W., et al. Nature 434(7034):724-731(2005)
  • Zhang, Z., et al. Genomics 81(5):468-480(2003)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This MRPL19 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 49-76 amino acids from the N-terminal region of human MRPL19.
NCBI Gene ID #:
9801
NCBI Official Name:
39S ribosomal protein L19, mitochondrial
NCBI Official Symbol:
MRPL19
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
34 kDa
Protein Accession #:
P49406
Protein GI Number:
92090636
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Obesity
Swissprot #:
P49406
User NOte:
Optimal dilutions for each application to be determined by the researcher.