HTR3A Antibody
Code | Size | Price |
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PSI-56-271-400ul | 400ul | £626.00 |
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Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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Further Information
Additional Names:
5-hydroxytryptamine receptor 3A, 5-HT3-A, 5-HT3A, 5-hydroxytryptamine receptor 3, 5-HT-3, 5-HT3R, Serotonin receptor 3A, Serotonin-gated ion channel receptor, HTR3A, 5HT3R, HTR3
Application Note:
For WB starting dilution is: 1:1000
Background:
The product of this gene belongs to the ligand-gated ion
channel receptor superfamily. This gene encodes subunit A of the
type 3 receptor for 5-hydroxytryptamine (serotonin), a biogenic
hormone that functions as a neurotransmitter, a hormone, and a
mitogen. This receptor causes fast, depolarizing responses in
neurons after activation. It appears that the heteromeric
combination of A and B subunits is necessary to provide the full
functional features of this receptor, since either subunit alone
results in receptors with very low conductance and response
amplitude. Alternatively spliced transcript variants encoding
different isoforms have been identified.
Background References:
- Gatt, J.M., et al. Biol. Psychiatry 68(9):818-824(2010)
- Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)
- Gatt, J.M., et al. Depress Anxiety 27(8):752-759(2010)
- Ruano, G., et al. Pharmacogenomics 11(7):959-971(2010)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This HTR3A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 30-58 amino acids from the N-terminal region of human HTR3A.
NCBI Gene ID #:
3359
NCBI Official Name:
5-hydroxytryptamine receptor 3A
NCBI Official Symbol:
HTR3A
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
55 kDa
Protein Accession #:
P46098
Protein GI Number:
1168222
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Obesity,Neuroscience
Swissprot #:
P46098
User NOte:
Optimal dilutions for each application to be determined by the researcher.