TTC8 Antibody

ProSci
Product Code: PSI-58-745
Product Group: Primary Antibodies
Supplier: ProSci
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PSI-58-745-400ul400ul£626.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Images

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Western blot analysis in 293 cell line lysates (35ug/lane).

Western blot analysis in 293 cell line lysates (35ug/lane).

Further Information

Additional Names:
Tetratricopeptide repeat protein 8, TPR repeat protein 8, Bardet-Biedl syndrome 8 protein, TTC8, BBS8
Application Note:
For WB starting dilution is: 1:1000
Background:
This gene encodes a protein that has been directly linked to Bardet-Biedl syndrome. The primary features of this syndrome include retinal dystrophy, obesity, polydactyly, renal abnormalities and learning disabilities. Experimentation in non-human eukaryotes suggests that this gene is expressed in ciliated cells and that it is involved in the formation of cilia. Alternate transcriptional splice variants have been characterized.
Background References:
  • Riazuddin, S.A., et al. Am. J. Hum. Genet. 86(5):805-812(2010)
  • Bin, J., et al. Hum. Mutat. 30 (7), E737-E746 (2009) :
  • Chung, W.K., et al. Hum. Hered. 67(3):193-205(2009)
  • Nachury, M.V., et al. Cell 129(6):1201-1213(2007)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This TTC8 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 18-46 amino acids from the N-terminal region of human TTC8.
NCBI Gene ID #:
123016
NCBI Official Name:
Tetratricopeptide repeat protein 8
NCBI Official Symbol:
TTC8
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
62 kDa
Protein Accession #:
Q8TAM2
Protein GI Number:
308153511
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Obesity,Neuroscience
Swissprot #:
Q8TAM2
User NOte:
Optimal dilutions for each application to be determined by the researcher.