5HT3E Antibody
| Code | Size | Price |
|---|
| PSI-55-244-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
- Flow Cytometry
- Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
5-hydroxytryptamine receptor 3E, 5-HT3-E, 5-HT3E, Serotonin receptor 3E, HTR3E
Application Note:
For WB starting dilution is: 1:1000
For FACS starting dilution is: 1:10~50
For FACS starting dilution is: 1:10~50
Background:
The product of this gene belongs to the ligand-gated ion
channel receptor superfamily. HTR3E encodes a subunit E of the
type 3 receptor for 5-hydroxytryptamine (serotonin), a biogenic
hormone that functions as a neurotransmitter, a hormone, and a
mitogen. This receptor causes fast, depolarizing responses in
neurons after activation. Genes encoding subunits C, D and E form a
cluster on chromosome 3. An alternative splice variant has been
described but its full length sequence has not been determined.
Background References:
- Walstab, J., et al. J. Biol. Chem. 285(35):26956-26965(2010)
- Hammer, C., et al. Pharmacogenomics 11(7):943-950(2010)
- Lennertz, L., et al. Eur Neuropsychopharmacol 20(6):414-420(2010)
- Goecke, T.W., et al. Acta Obstet Gynecol Scand 89(1):7-14(2010)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This 5HT3E antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 126-154 amino acids from the Central region of human 5HT3E.
NCBI Gene ID #:
285242
NCBI Official Name:
5-hydroxytryptamine receptor 3E
NCBI Official Symbol:
HTR3E
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
51 kDa
Protein Accession #:
A5X5Y0
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Obesity,Neuroscience
Swissprot #:
A5X5Y0
User NOte:
Optimal dilutions for each application to be determined by the researcher.