HTR7 Antibody

ProSci
Product Code: PSI-58-454
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-58-454-400ul400ul£626.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Images

1 / 1
Western blot analysis in MDA-MB231 cell line lysates (35ug/lane).

Western blot analysis in MDA-MB231 cell line lysates (35ug/lane).

Further Information

Additional Names:
5-hydroxytryptamine receptor 7, 5-HT-7, 5-HT7, 5-HT-X, Serotonin receptor 7, HTR7
Application Note:
For WB starting dilution is: 1:1000
Background:
The neurotransmitter, serotonin, is thought to play a role in various cognitive and behavioral functions. The serotonin receptor encoded by this gene belongs to the superfamily of G protein-coupled receptors and the gene is a candidate locus for involvement in autistic disorder and other neuropsychiatric disorders. Three splice variants have been identified which encode proteins that differ in the length of their carboxy terminal ends.
Background References:
  • Ruano, G., et al. Pharmacogenomics 11(7):959-971(2010)
  • Pinheiro, A.P., et al. Am. J. Med. Genet.Neuropsychiatr. Genet. 153B (5), 1070-1080 (2010) :
  • Corominas, R., et al. Am. J. Med. Genet.Neuropsychiatr. Genet. 153B (1), 177-184 (2010) :
  • Wei, Z., et al. Prog. Neuropsychopharmacol. Biol. Psychiatry 33(3):547-551(2009)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This HTR7 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 405-433 amino acids from the C-terminal region of human HTR7.
NCBI Gene ID #:
3363
NCBI Official Name:
5-hydroxytryptamine receptor 7
NCBI Official Symbol:
HTR7
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
54 kDa
Protein Accession #:
P34969
Protein GI Number:
8488960
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Obesity,Neuroscience,Growth Factor
Swissprot #:
P34969
User NOte:
Optimal dilutions for each application to be determined by the researcher.