ATP1A3 Antibody
| Code | Size | Price |
|---|
| PSI-60-827-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
Sodium/potassium-transporting ATPase subunit alpha-3, Na(+)/K(+) ATPase alpha-3 subunit, Na(+)/K(+) ATPase alpha(III) subunit, Sodium pump subunit alpha-3, ATP1A3
Application Note:
For WB starting dilution is: 1:1000
Background:
The protein encoded by this gene belongs to the family of
P-type cation transport ATPases, and to the subfamily of Na+/K+
-ATPases. Na+/K+ -ATPase is an integral membrane protein
responsible for establishing and maintaining the electrochemical
gradients of Na and K ions across the plasma membrane. These
gradients are essential for osmoregulation, for sodium-coupled
transport of a variety of organic and inorganic molecules, and for
electrical excitability of nerve and muscle. This enzyme is
composed of two subunits, a large catalytic subunit (alpha) and a
smaller glycoprotein subunit (beta). The catalytic subunit of
Na+/K+ -ATPase is encoded by multiple genes. This gene encodes an
alpha 3 subunit.
Background References:
- Einholm, A.P., et al. J. Biol. Chem. 285(34):26245-26254(2010)
- Floyd, R.V., et al. Reprod Sci 17(4):366-376(2010)
- Hauck, C., et al. Eur. J. Pharmacol. 622 (1-3), 7-14 (2009) :
- Blanco-Arias, P., et al. Hum. Mol. Genet. 18(13):2370-2377(2009)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Predicted species reactivity based on immunogen sequence: Chicken, Mouse, Rat
Immunogen:
This ATP1A3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 805-833 amino acids from the Central region of human ATP1A3.
NCBI Gene ID #:
478
NCBI Official Name:
Sodium/potassium-transporting ATPase subunit alpha-3
NCBI Official Symbol:
ATP1A3
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
112 kDa
Protein Accession #:
P13637
Protein GI Number:
116241260
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Obesity,Neuroscience,Signal Transduction
Swissprot #:
P13637
User NOte:
Optimal dilutions for each application to be determined by the researcher.