HDC Antibody
| Code | Size | Price |
|---|
| PSI-57-535-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
Histidine decarboxylase, HDC, HDC
Application Note:
For WB starting dilution is: 1:1000
Background:
This gene encodes a member of the group II decarboxylase
family and forms a homodimer that converts L-histidine to histamine
in a pyridoxal phosphate dependent manner. Histamine regulates
several physiologic processes, including neurotransmission, gastric
acid secretion,inflamation, and smooth muscle tone.
Background References:
- Gervasini, G., et al. Allergy (2010) In press :
- Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :
- Ercan-Sencicek, A.G., et al. N. Engl. J. Med. 362(20):1901-1908(2010)
- Jeong, H.J., et al. Cell. Mol. Life Sci. 66(7):1309-1319(2009)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This HDC antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 147-178 amino acids from the N-terminal region of human HDC.
NCBI Gene ID #:
3067
NCBI Official Name:
Histidine decarboxylase
NCBI Official Symbol:
HDC
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
74 kDa
Protein Accession #:
P19113
Protein GI Number:
1352220
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Obesity,Neuroscience,Signal Transduction
Swissprot #:
P19113
User NOte:
Optimal dilutions for each application to be determined by the researcher.