ELOVL4 Antibody

ProSci
Product Code: PSI-58-405
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-58-405-400ul400ul£626.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Images

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Western Blot at 1:1000 dilution Lane 1: human testis lysate Lane 2: Y79 whole cell lysate Lysates/proteins at 20 ug per lane.
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Western blot analysis in 293 cell line lysates (35ug/lane).

Western Blot at 1:1000 dilution Lane 1: human testis lysate Lane 2: Y79 whole cell lysate Lysates/proteins at 20 ug per lane.
Western blot analysis in 293 cell line lysates (35ug/lane).

Further Information

Additional Names:
Elongation of very long chain fatty acids protein 4, 3-keto acyl-CoA synthase ELOVL4, ELOVL fatty acid elongase 4, ELOVL FA elongase 4, Very-long-chain 3-oxoacyl-CoA synthase 4, ELOVL4
Application Note:
For WB starting dilution is: 1:1000
Background:
ELOVL4 is a membrane-bound protein which is a member of the ELO family, proteins which participate in the biosynthesis of fatty acids. Consistent with the expression of the encoded protein in photoreceptor cells of the retina, mutations and small deletions in this gene are associated with Stargardt-like macular dystrophy (STGD3) and autosomal dominant Stargardt-like macular dystrophy (ADMD), also referred to as autosomal dominant atrophic macular degeneration.
Background References:
  • Kasperaviciute, D., et al. Brain 133 (PT 7), 2136-2147 (2010) :
  • Vasireddy, V., et al. Prog Retin Eye Res 29(3):191-207(2010)
  • Gu, H., et al. Zhonghua Yan Ke Za Zhi 46(2):125-128(2010)
  • DeAngelis, M.M., et al. Arch. Ophthalmol. 125(1):49-54(2007)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Predicted species reactivity based on immunogen sequence: Monkey
Immunogen:
This ELOVL4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 286-314 amino acids from the C-terminal region of human ELOVL4.
NCBI Gene ID #:
6785
NCBI Official Name:
Elongation of very long chain fatty acids protein 4
NCBI Official Symbol:
ELOVL4
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
37 kDa
Protein Accession #:
Q9GZR5
Protein GI Number:
20137966
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Obesity,Neuroscience,Signal Transduction
Swissprot #:
Q9GZR5
User NOte:
Optimal dilutions for each application to be determined by the researcher.