CHST5 Antibody
| Code | Size | Price |
|---|
| PSI-60-215-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
Carbohydrate sulfotransferase 5, 282-, Galactose/N-acetylglucosamine/N-acetylglucosamine 6-O-sulfotransferase 4-alpha, GST4-alpha, Intestinal N-acetylglucosamine-6-O-sulfotransferase, I-GlcNAc6ST, Intestinal GlcNAc-6-sulfotransferase, hIGn6ST, N-acetylglucosamine 6-O-sulfotransferase 3, GlcNAc6ST-3, Gn6st-3, CHST5
Application Note:
For WB starting dilution is: 1:1000
Background:
The carbohydrates of glycoconjugates are highly diverse
structures with variation in monosaccharide composition, glycosidic
linkage positions, and branching of chains. Further diversity is
added by the covalent addition of sulfate moieties to particular
hydroxyl groups and amino groups of saccharides. The sulfate
modifications of glycoproteins can be extensive in amount and
frequently occur at high density. They can have a profound effect
on the physiochemical properties of the glycoconjugates, at least
in part through the addition of negative charge. Carbohydrate
sulfation plays a critical role in many biologic processes. CHST5
belongs to the GST family of sulfotransferases, which also includes
CHST1 (MIM 603797), CHST2 (MIM 603798), CHST3 (MIM 603799), and
LSST. These enzymes are 6-O-sulfotransferases, which add sulfate to
C6 of galactose (Gal), N-acetylgalactosamine (GalNAc), or
N-acetylglucosamine (GlcNAc) (Lee et al., 1999 [PubMed
10491328]).
Background References:
- Liu, C.Y., et al. Carcinogenesis 31(7):1259-1263(2010)
- Dastani, Z., et al. Eur. J. Hum. Genet. 18(3):342-347(2010)
- Saito, A., et al. J. Hum. Genet. 54(6):317-323(2009)
- Kitayama, K., et al. J. Biol. Chem. 282(41):30085-30096(2007)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This CHST5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 275-302 amino acids from the C-terminal region of human CHST5.
NCBI Gene ID #:
23563
NCBI Official Name:
Carbohydrate sulfotransferase 5
NCBI Official Symbol:
CHST5
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
46 kDa
Protein Accession #:
Q9GZS9
Protein GI Number:
239938912
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Obesity,Neuroscience,Signal Transduction
Swissprot #:
Q9GZS9
User NOte:
Optimal dilutions for each application to be determined by the researcher.