TRPM4 Antibody
| Code | Size | Price |
|---|
| PSI-58-239-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
Transient receptor potential cation channel subfamily M member 4, hTRPM4, Calcium-activated non-selective cation channel 1, Long transient receptor potential channel 4, LTrpC-4, LTrpC4, Melastatin-4, TRPM4, LTRPC4
Application Note:
For WB starting dilution is: 1:1000
Background:
The protein encoded by this gene is a calcium-activated
nonselective ion channel that mediates transport of monovalent
cations across membranes, thereby depolarizing the membrane. The
activity of the encoded protein increases with increasing
intracellular calcium concentration, but this channel does not
transport calcium. Two transcript variants encoding different
isoforms have been found for this gene.
Background References:
- Liu, H., et al. Circ Cardiovasc Genet 3(4):374-385(2010)
- Yoo, J.C., et al. Biochem. Biophys. Res. Commun. 391(1):806-811(2010)
- Kruse, M., et al. J. Clin. Invest. 119(9):2737-2744(2009)
- Marigo, V., et al. Mol. Cell. Endocrinol. 299(2):194-203(2009)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This TRPM4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1121-1149 amino acids from the C-terminal region of human TRPM4.
NCBI Gene ID #:
54795
NCBI Official Name:
Transient receptor potential cation channel subfamily M member 4
NCBI Official Symbol:
TRPM4
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
134 kDa
Protein Accession #:
Q8TD43
Protein GI Number:
74715868
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Obesity,Neuroscience,Signal Transduction
Swissprot #:
Q8TD43
User NOte:
Optimal dilutions for each application to be determined by the researcher.