PNPO Antibody
| Code | Size | Price |
|---|
| PSI-63-923-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
Pyridoxine-5'-phosphate oxidase, Pyridoxamine-phosphate oxidase, PNPO
Application Note:
For WB starting dilution is: 1:1000
Background:
The enzyme encoded by this gene catalyzes the terminal, rate-limiting step in the synthesis of pyridoxal 5'-phosphate, also known as vitamin B6. Vitamin B6 is a required co-factor for enzymes involved in both homocysteine metabolism and synthesis of neurotransmitters such as catecholamine.
Background References:
- Musayev, F.N., et al. J. Biol. Chem. 284(45):30949-30956(2009)
- Khayat, M., et al. Mol. Genet. Metab. 94(4):431-434(2008)
- Song, H., et al. Schizophr. Res. 97 (1-3), 264-270 (2007) :
- Mills, P.B., et al. Hum. Mol. Genet. 14(8):1077-1086(2005)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This PNPO antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 232-261 amino acids from the C-terminal region of human PNPO.
NCBI Gene ID #:
55163
NCBI Official Name:
Pyridoxine-5'-phosphate oxidase
NCBI Official Symbol:
PNPO
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
30 kDa
Protein Accession #:
Q9NVS9
Protein GI Number:
37082126
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Obesity,Neuroscience,Signal Transduction
Swissprot #:
Q9NVS9
User NOte:
Optimal dilutions for each application to be determined by the researcher.