APOER2 Antibody

ProSci
Product Code: PSI-62-148
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-62-148-400ul400ul£626.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
  • Immunohistochemistry- Paraffin Embedded (IHC-P)
  • Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Images

1 / 2
Antibody is used in Western blot to detect LRP8 in placenta cell lysate.
2 / 2
Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. BC = breast carcinoma; HC = hepatocarcinoma.

Antibody is used in Western blot to detect LRP8 in placenta cell lysate.
Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. BC = breast carcinoma; HC = hepatocarcinoma.

Further Information

Additional Names:
Low-density lipoprotein receptor-related protein 8, LRP-8, Apolipoprotein E receptor 2, LRP8, APOER2
Application Note:
For WB starting dilution is: 1:1000

For IHC-P starting dilution is: 1:50~100
Background:
LPR8 is an apolipoprotein E receptor, a member of the low density lipoprotein receptor (LDLR) family. Apolipoprotein E is a small lipophilic plasma protein and a component of lipoproteins such as chylomicron remnants, very low density lipoprotein (VLDL), and high density lipoprotein (HDL). The apolipoprotein E receptor is involved in cellular recognition and internalization of these lipoproteins.
Background References:
  • Li, X., et al., Biochemistry 42(35):10406-10417 (2003).
  • Sun, X.M., et al., J. Biol. Chem. 278(22):19926-19932 (2003).
  • Korschineck, I., et al., J. Biol. Chem. 276(16):13192-13197 (2001).
  • Sun, X.M., et al., Eur. J. Biochem. 262(1):230-239 (1999).
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This APOER2 (LRP8) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 934-963 amino acids from the C-terminal region of human APOER2 (LRP8).
NCBI Gene ID #:
7804
NCBI Official Name:
Low-density lipoprotein receptor-related protein 8
NCBI Official Symbol:
LRP8
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
106 kDa
Protein Accession #:
Q14114
Protein GI Number:
259016389
Purification:
This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis
Research Area:
Obesity,Neuroscience,Signal Transduction
Swissprot #:
Q14114
User NOte:
Optimal dilutions for each application to be determined by the researcher.