IMPDH1 Antibody
| Code | Size | Price |
|---|
| PSI-57-919-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
- Immunohistochemistry- Paraffin Embedded (IHC-P)
- Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
Inosine-5'-monophosphate dehydrogenase 1 {ECO:0000255|HAMAP-Rule:MF_03156}, IMP dehydrogenase 1 {ECO:0000255|HAMAP-Rule:MF_03156}, IMPD 1 {ECO:0000255|HAMAP-Rule:MF_03156}, IMPDH 1 {ECO:0000255|HAMAP-Rule:MF_03156}, 111205 {ECO:0000255|HAMAP-Rule:MF_03156}, IMPDH-I, IMPDH1 {ECO:0000255|HAMAP-Rule:MF_03156}, IMPD1
Application Note:
For WB starting dilution is: 1:1000
For IHC-P starting dilution is: 1:10~50
For IHC-P starting dilution is: 1:10~50
Background:
The protein encoded by this gene acts as a homotetramer to
regulate cell growth. The encoded protein is an enzyme that
catalyzes the synthesis of xanthine monophosphate (XMP) from
inosine-5'-monophosphate (IMP). This is the rate-limiting step in
the de novo synthesis of guanine nucleotides. Defects in this gene
are a cause of retinitis pigmentosa type 10 (RP10). Several
transcript variants encoding different isoforms have been found for
this gene.
Background References:
- Ohmann, E.L., et al. Pediatr Transplant 14(7):891-895(2010)
- Gensburger, O., et al. Pharmacogenet. Genomics 20(9):537-543(2010)
- Kagaya, H., et al. Basic Clin. Pharmacol. Toxicol. 107(2):631-636(2010)
- Ohmann, E.L., et al. J. Heart Lung Transplant. 29(5):509-516(2010)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Predicted species reactivity based on immunogen sequence: Bovine, Zebrafish, Mouse, Rat
Immunogen:
This IMPDH1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 84-113 amino acids from the N-terminal region of human IMPDH1.
NCBI Gene ID #:
3614
NCBI Official Name:
Inosine-5'-monophosphate dehydrogenase 1 {ECO:0000255|HAMAP-Rule:MF_03156}
NCBI Official Symbol:
IMPDH1
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
55 kDa
Protein Accession #:
P20839
Protein GI Number:
25014074
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Obesity,Neuroscience,Signal Transduction
Swissprot #:
P20839
User NOte:
Optimal dilutions for each application to be determined by the researcher.