SLC5A12 Antibody
Code | Size | Price |
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PSI-55-133-400ul | 400ul | £626.00 |
Quantity:
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Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
- Fluorescence-activated cell sorting (FACS)
- Immunohistochemistry- Paraffin Embedded (IHC-P)
- Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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Further Information
Additional Names:
Sodium-coupled monocarboxylate transporter 2, Electroneutral sodium monocarboxylate cotransporter, Low-affinity sodium-lactate cotransporter, Solute carrier family 5 member 12, SLC5A12, SMCT2
Application Note:
For WB starting dilution is: 1:2000
For IHC-P starting dilution is: 1:50~100
For FACS starting dilution is: 1:10~50
For IHC-P starting dilution is: 1:50~100
For FACS starting dilution is: 1:10~50
Background:
Normal blood lactate is maintained at about 1.5 mM, and
little filtered lactate is excreted in urine. Reabsorption of
lactate is mediated by the low-affinity Na(+)-coupled lactate
transporter SLC5A12 in the initial part of the proximal tubule and
by the high-affinity Na(+)-coupled lactate transporter SLC5A8 (MIM
608044) in the distal proximal tubule (Gopal et al., 2007 [PubMed
17692818]).
Background References:
- Gopal, E., et al. Biochim. Biophys. Acta 1768(11):2690-2697(2007)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This SLC5A12 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 576-605 amino acids from the C-terminal region of human SLC5A12.
NCBI Gene ID #:
159963
NCBI Official Name:
Sodium-coupled monocarboxylate transporter 2
NCBI Official Symbol:
SLC5A12
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
68 kDa
Protein Accession #:
Q1EHB4
Protein GI Number:
189046187
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Obesity,Neuroscience,Signal Transduction
Swissprot #:
Q1EHB4
User NOte:
Optimal dilutions for each application to be determined by the researcher.