CB1 Antibody
| Code | Size | Price |
|---|
| PSI-60-631-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
Cannabinoid receptor 1, CB-R, CB1, CANN6, CNR1, CNR
Application Note:
For WB starting dilution is: 1:1000
Background:
This gene encodes one of two cannabinoid receptors. The
cannabinoids, principally delta-9-tetrahydrocannabinol and
synthetic analogs, are psychoactive ingredients of marijuana. The
cannabinoid receptors are members of the guanine-nucleotide-binding
protein (G-protein) coupled receptor family, which inhibit
adenylate cyclase activity in a dose-dependent, stereoselective and
pertussis toxin-sensitive manner. The two receptors have been found
to be involved in the cannabinoid-induced CNS effects (including
alterations in mood and cognition) experienced by users of
marijuana. Multiple transcript variants encoding two different
protein isoforms have been described for this gene. [provided by
RefSeq].
Background References:
- Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)
- Van Laere, K., et al. J. Nucl. Med. 51(9):1413-1417(2010)
- Larrinaga, G., et al. Histol. Histopathol. 25(9):1133-1138(2010)
- Monteleone, P., et al.Clin Psychopharmacol 30(4):441-445(2010)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This CB1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 161-187 amino acids from the Central region of human CB1.
NCBI Gene ID #:
1268
NCBI Official Name:
Cannabinoid receptor 1
NCBI Official Symbol:
CNR1
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
53 kDa
Protein Accession #:
P21554
Protein GI Number:
115562
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Obesity,Neuroscience,Signal Transduction,Growth Factor
Swissprot #:
P21554
User NOte:
Optimal dilutions for each application to be determined by the researcher.