GNMT Antibody
| Code | Size | Price |
|---|
| PSI-55-405-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
Glycine N-methyltransferase, GNMT
Application Note:
For WB starting dilution is: 1:1000
Background:
Glycine N-methyltransferase catalyzes the synthesis of N-methylglycine (sarcosine) from glycine using S-adenosylmethionine (AdoMet) as the methyl donor. GNMT acts as an enzyme to regulate the ratio of S-adenosylmethionine to S-adenosylhomocysteine (AdoHcy) and participates in the detoxification pathway in liver cells.
Background References:
- Augoustides-Savvopoulou, P., et al., J. Inherit. Metab. Dis. 26(8):745-759 (2003). Tseng, T.L., et al., Cancer Res. 63(3):647-654 (2003). Luka, Z., et al., Hum. Genet. 110(1):68-74 (2002). Strausberg RL, et al., Proc. Natl. Acad. Sci. U.S.A. 99(26):16899-16903 (2002). Mudd, S.H., et al., J. Inherit. Metab. Dis. 24(4):448-464 (2001).
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This GNMT antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 218-248 amino acids from the C-terminal region of human GNMT.
NCBI Gene ID #:
27232
NCBI Official Name:
Glycine N-methyltransferase
NCBI Official Symbol:
GNMT
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
33 kDa
Protein Accession #:
Q14749
Protein GI Number:
12644416
Purification:
This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis
Research Area:
Obesity,Signal Transduction
Swissprot #:
Q14749
User NOte:
Optimal dilutions for each application to be determined by the researcher.