GCHFR Antibody
| Code | Size | Price |
|---|
| PSI-60-235-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
GTP cyclohydrolase 1 feedback regulatory protein, GFRP, GTP cyclohydrolase I feedback regulatory protein, p35, GCHFR, GFRP
Application Note:
For WB starting dilution is: 1:1000
Background:
GTP cyclohydrolase I feedback regulatory protein binds to and mediates tetrahydrobiopterin inhibition of GTP cyclohydrolase I. The regulatory protein, GCHFR, consists of a homodimer. It is postulated that GCHFR may play a role in regulating phenylalanine metabolism in the liver and in the production of biogenic amine neurotransmitters and nitric oxide.
Background References:
- Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010) McHugh, P.C., et al. Pharmacogenomics J. (2010) In pressLi, L., et al. Circ. Res. 106(2):328-336(2010) Talmud, P.J., et al. Am. J. Hum. Genet. 85(5):628-642(2009) Schnetz-Boutaud, N.C., et al. Genes Brain Behav. 8(8):753-757(2009)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Predicted species reactivity based on immunogen sequence: Bovine
Immunogen:
This GCHFR antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 38-66 amino acids from the C-terminal region of human GCHFR.
NCBI Gene ID #:
2644
NCBI Official Name:
GTP cyclohydrolase 1 feedback regulatory protein
NCBI Official Symbol:
GCHFR
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
10 kDa
Protein Accession #:
P30047
Protein GI Number:
2506906
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Obesity,Signal Transduction
Swissprot #:
P30047
User NOte:
Optimal dilutions for each application to be determined by the researcher.