SCO2 Antibody
Code | Size | Price |
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PSI-59-349-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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Further Information
Additional Names:
Protein SCO2 homolog, mitochondrial, SCO2
Application Note:
For WB starting dilution is: 1:1000
Background:
Cytochrome c oxidase (COX) catalyzes the transfer of
electrons from cytochrome c to molecular oxygen, which helps to
maintain the proton gradient across the inner mitochondrial
membrane that is necessary for aerobic ATP production. Human COX is
a multimeric protein complex that requires several assembly
factors; this gene encodes one of the COX asembly factors. The
encoded protein is a metallochaperone that is involved in the
biogenesis of cytochrome c oxidase subunit II. Mutations in this
gene are associated with fatal infantile encephalocardiomyopathy.
Background References:
- Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)
- Foltopoulou, P.F., et al. Biochim. Biophys. Acta 1802(6):497-508(2010)
- Pronicki, M., et al. Eur. J. Paediatr. Neurol. 14(3):253-260(2010)
- Kamatani, Y., et al. Nat. Genet. 42(3):210-215(2010)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Predicted species reactivity based on immunogen sequence: Bovine, Mouse
Immunogen:
This SCO2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 196-224 amino acids from the C-terminal region of human SCO2.
NCBI Gene ID #:
9997
NCBI Official Name:
Protein SCO2 homolog, mitochondrial
NCBI Official Symbol:
SCO2
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
30 kDa
Protein Accession #:
O43819
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Obesity,Signal Transduction
Swissprot #:
O43819
User NOte:
Optimal dilutions for each application to be determined by the researcher.