NAT1 Antibody

ProSci
Product Code: PSI-56-897
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-56-897-400ul400ul£626.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Images

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Western blot analysis in A375 cell line lysates (35ug/lane).

Western blot analysis in A375 cell line lysates (35ug/lane).

Further Information

Additional Names:
Arylamine N-acetyltransferase 1, Arylamide acetylase 1, Monomorphic arylamine N-acetyltransferase, MNAT, N-acetyltransferase type 1, NAT-1, NAT1, AAC1
Application Note:
For WB starting dilution is: 1:1000
Background:
This gene is one of two arylamine N-acetyltransferase (NAT) genes in the human geneome, and is orthologous to the mouse and rat Nat2 genes. The enzyme encoded by this gene catalyzes the transfer of an acetyl group from acetyl-CoA to various arylamine and hydrazine substrates. This enzyme helps metabolize drugs and other xenobiotics, and functions in folate catabolism. Multiple transcript variants encoding different isoforms have been found for this gene.
Background References:
  • Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)
  • Jugessur, A., et al. PLoS ONE(7), E11493 (2010) :
  • Minchin, R.F., et al. Int. J. Biochem. Cell Biol. 39(11):1999-2005(2007)
  • Barker, D.F., et al. Pharmacogenet. Genomics 16(7):515-525(2006)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Predicted species reactivity based on immunogen sequence: Rb
Immunogen:
This NAT1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 102-130 amino acids from the Central region of human NAT1.
NCBI Gene ID #:
9
NCBI Official Name:
Arylamine N-acetyltransferase 1
NCBI Official Symbol:
NAT1
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
34 kDa
Protein Accession #:
P18440
Protein GI Number:
114234
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Obesity,Signal Transduction
Swissprot #:
P18440
User NOte:
Optimal dilutions for each application to be determined by the researcher.