PLA2G12A Antibody
| Code | Size | Price |
|---|
| PSI-58-615-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
Group XIIA secretory phospholipase A2, GXII sPLA2, sPLA2-XII, Phosphatidylcholine 2-acylhydrolase 12A, PLA2G12A, PLA2G12
Application Note:
For WB starting dilution is: 1:1000
Background:
Secreted phospholipase A2 (sPLA2) enzymes liberate
arachidonic acid from phospholipids for production of eicosanoids
and exert a variety of physiologic and pathologic effects. Group
XII sPLA2s, such as PLA2G12A, have relatively low specific activity
and are structurally and functionally distinct from other sPLA2s
(Gelb et al., 2000 [PubMed 11031251]).
Background References:
- Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)
- Kalsi, G., et al. Hum. Mol. Genet. 19(12):2497-2506(2010)
- Chen, W., et al. Proc. Natl. Acad. Sci. U.S.A. 107(16):7401-7406(2010)
- Hosgood, H.D. III, et al. Occup Environ Med 66(12):848-853(2009)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This PLA2G12A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 55-83 amino acids from the Central region of human PLA2G12A.
NCBI Gene ID #:
81579
NCBI Official Name:
Group XIIA secretory phospholipase A2
NCBI Official Symbol:
PLA2G12A
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
21 kDa
Protein Accession #:
Q9BZM1
Protein GI Number:
20143881
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Obesity,Signal Transduction
Swissprot #:
Q9BZM1
User NOte:
Optimal dilutions for each application to be determined by the researcher.