FADS3 Antibody
Code | Size | Price |
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PSI-59-763-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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Further Information
Additional Names:
Fatty acid desaturase 3, 11419-, Cytochrome b5-related protein, FADS3, CYB5RP
Application Note:
For WB starting dilution is: 1:1000
Background:
The protein encoded by this gene is a member of the fatty
acid desaturase (FADS) gene family. Desaturase enzymes regulate
unsaturation of fatty acids through the introduction of double
bonds between defined carbons of the fatty acyl chain. FADS family
members are considered fusion products composed of an N-terminal
cytochrome b5-like domain and a C-terminal multiple
membrane-spanning desaturase portion, both of which are
characterized by conserved histidine motifs. This gene is clustered
with family members FADS1 and FADS2 at 11q12-q13.1; this cluster is
thought to have arisen evolutionarily from gene duplication based
on its similar exon/intron organization.
Background References:
- Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)
- Mathias, R.A., et al. J. Lipid Res. 51(9):2766-2774(2010)
- Barber, M.J., et al. PLoS ONE(3), E9763 (2010) :
- Talmud, P.J., et al. Am. J. Hum. Genet. 85(5):628-642(2009)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Predicted species reactivity based on immunogen sequence: Mouse, Rat
Immunogen:
This FADS3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 328-355 amino acids from the C-terminal region of human FADS3.
NCBI Gene ID #:
3995
NCBI Official Name:
Fatty acid desaturase 3
NCBI Official Symbol:
FADS3
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
51 kDa
Protein Accession #:
Q9Y5Q0
Protein GI Number:
74762790
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Obesity,Signal Transduction
Swissprot #:
Q9Y5Q0
User NOte:
Optimal dilutions for each application to be determined by the researcher.