ATP2A2 Antibody
| Code | Size | Price |
|---|
| PSI-58-877-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
Sarcoplasmic/endoplasmic reticulum calcium ATPase 2, SERCA2, SR Ca(2+)-ATPase 2, Calcium pump 2, Calcium-transporting ATPase sarcoplasmic reticulum type, slow twitch skeletal muscle isoform, Endoplasmic reticulum class 1/2 Ca(2+) ATPase, ATP2A2, ATP2B
Application Note:
For WB starting dilution is: 1:1000
Background:
This gene encodes one of the SERCA Ca(2+)-ATPases, which
are intracellular pumps located in the sarcoplasmic or endoplasmic
reticula of muscle cells. This enzyme catalyzes the hydrolysis of
ATP coupled with the translocation of calcium from the cytosol into
the sarcoplasmic reticulum lumen, and is involved in regulation of
the contraction/relaxation cycle. Mutations in this gene cause
Darier-White disease, also known as keratosis follicularis, an
autosomal dominant skin disorder characterized by loss of adhesion
between epidermal cells and abnormal keratinization. Alternative
splicing results in multiple transcript variants encoding different
isoforms.
Background References:
- Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)
- Tuusa, J.T., et al. FEBS J. 277(13):2815-2829(2010)
- Godic, A., et al. EurDermatol 20(3):271-275(2010)
- Godic, A., et al. J. Am. Acad. Dermatol. 62(5):819-823(2010)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This ATP2A2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 374-403 amino acids from the Central region of human ATP2A2.
NCBI Gene ID #:
488
NCBI Official Name:
Sarcoplasmic/endoplasmic reticulum calcium ATPase 2
NCBI Official Symbol:
ATP2A2
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
115 kDa
Protein Accession #:
P16615
Protein GI Number:
114312
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Obesity,Signal Transduction
Swissprot #:
P16615
User NOte:
Optimal dilutions for each application to be determined by the researcher.