TFR2 Antibody
| Code | Size | Price |
|---|
| PSI-56-432-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
Transferrin receptor protein 2, TfR2, TFR2
Application Note:
For WB starting dilution is: 1:1000
Background:
This gene is a member of the transferrin receptor-like
family and encodes a single-pass type II membrane protein with a
protease associated (PA) domain, an M28 peptidase domain and a
transferrin receptor-like dimerization domain. This protein
mediates cellular uptake of transferrin-bound iron and mutations in
this gene have been associated with hereditary hemochromatosis type
III. Alternatively spliced variants which encode different protein
isoforms have been described; however, not all variants have been
fully characterized.
Background References:
- Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)
- Ucisik-Akkaya, E., et al. Mol. Hum. Reprod. 16(10):770-777(2010)
- Ikuta, K., et al. J. Mol. Biol. 397(2):375-384(2010)
- Talmud, P.J., et al. Am. J. Hum. Genet. 85(5):628-642(2009)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This TFR2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 674-703 amino acids from the C-terminal region of human TFR2.
NCBI Gene ID #:
7036
NCBI Official Name:
Transferrin receptor protein 2
NCBI Official Symbol:
TFR2
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
89 kDa
Protein Accession #:
Q9UP52
Protein GI Number:
20140912
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Obesity,Signal Transduction
Swissprot #:
Q9UP52
User NOte:
Optimal dilutions for each application to be determined by the researcher.