ODC1 Antibody
Code | Size | Price |
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PSI-57-425-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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Further Information
Additional Names:
Ornithine decarboxylase, ODC, ODC1
Application Note:
For WB starting dilution is: 1:1000
Background:
This gene encodes the rate-limiting enzyme of the
polyamine biosynthesis pathway which catalyzes ornithine to
putrescine. The activity level for the enzyme varies in response to
growth-promoting stimuli and exhibits a high turnover rate in
comparison to other mammalian proteins. Originally localized to
both chromosomes 2 and 7, the gene encoding this enzyme has been
determined to be located on 2p25, with a pseudogene located on
7q31-qter.
Background References:
- Chaturvedi, R., et al. Gastroenterology 139(5):1686-1698(2010)
- Zell, J.A., et al. J. Natl. Cancer Inst. 102(19):1513-1516(2010)
- Geerts, D., et al. Int. J. Cancer 126(9):2012-2024(2010)
- Hughes, D., et al. Colorectal Dis (2010) In press :
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Predicted species reactivity based on immunogen sequence: Bovine
Immunogen:
This ODC1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 323-352 amino acids from the C-terminal region of human ODC1.
NCBI Gene ID #:
4953
NCBI Official Name:
Ornithine decarboxylase
NCBI Official Symbol:
ODC1
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
51 kDa
Protein Accession #:
P11926
Protein GI Number:
118377
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Obesity,Signal Transduction
Swissprot #:
P11926
User NOte:
Optimal dilutions for each application to be determined by the researcher.