CBR4 Antibody
| Code | Size | Price |
|---|
| PSI-59-253-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
Carbonyl reductase family member 4, 1---, 3-oxoacyl-[acyl-carrier-protein] reductase, 111-, Quinone reductase CBR4, CBR4
Application Note:
For WB starting dilution is: 1:1000
Background:
The heteroteramer with HSD17B8 has NADH-dependent 3-ketoacyl-acyl carrier protein reductase activity. May play a role in biosynthesis of fatty acids in mitochondria. The homotetramer may act as NADPH-dependent quinone reductase. Has broad substrate specificity and reduces 9,10-phenanthrenequinone, 1,4-benzoquinone and various other o-quinones and p-quinones (in vitro).
Background References:
- Chen, Z., et al. FASEB J. 23(11):3682-3691(2009)
- Persson, B., et al. Chem. Biol. Interact. 178 (1-3), 94-98 (2009) :
- Endo, S., et al. Biochem. Biophys. Res. Commun. 377(4):1326-1330(2008)
- Lamesch, P., et al. Genomics 89(3):307-315(2007)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This CBR4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 178-205 amino acids from the C-terminal region of human CBR4.
NCBI Gene ID #:
84869
NCBI Official Name:
Carbonyl reductase family member 4
NCBI Official Symbol:
CBR4
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
25 kDa
Protein Accession #:
Q8N4T8
Protein GI Number:
269849708
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Obesity,Signal Transduction
Swissprot #:
Q8N4T8
User NOte:
Optimal dilutions for each application to be determined by the researcher.