AKR1E2 Antibody

ProSci
Product Code: PSI-60-077
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-60-077-400ul400ul£626.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Images

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Western blot analysis in A549 cell line lysates (35ug/lane).

Western blot analysis in A549 cell line lysates (35ug/lane).

Further Information

Additional Names:
5-anhydro-D-fructose reductase, AF reductase, Aldo-keto reductase family 1 member C-like protein 2, Aldo-keto reductase family 1 member E2, LoopADR, Testis-specific protein, hTSP, AKR1E2, AKR1CL2, AKRDC1
Application Note:
For WB starting dilution is: 1:1000
Background:
AKR1E2 catalyzes the NADPH-dependent reduction of 1,5-anhydro-D-fructose (AF) to 1,5-anhydro-D-glucitol. Can also catalyze the reduction of various aldehydes and quinones (By similarity). Has low NADPH-dependent reductase activity towards 9,10-phenanthrenequinone (in vitro).
Background References:
  • Clancy, R.M., et al. Arthritis Rheum. 62(11):3415-3424(2010)
  • Lamesch, P., et al. Genomics 89(3):307-315(2007)
  • Grupe, A., et al. Am. J. Hum. Genet. 78(1):78-88(2006)
  • Azuma, Y., et al. Mol. Hum. Reprod. 10(7):527-533(2004)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Predicted species reactivity based on immunogen sequence: Monkey
Immunogen:
This AKR1E2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 291-320 amino acids from the C-terminal region of human AKR1E2.
NCBI Gene ID #:
83592
NCBI Official Name:
1,5-anhydro-D-fructose reductase
NCBI Official Symbol:
AKR1E2
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
37 kDa
Protein Accession #:
Q96JD6
Protein GI Number:
269849539
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Obesity,Signal Transduction
Swissprot #:
Q96JD6
User NOte:
Optimal dilutions for each application to be determined by the researcher.