NMNAT3 Antibody
| Code | Size | Price |
|---|
| PSI-57-468-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
Nicotinamide mononucleotide adenylyltransferase 3, NMN adenylyltransferase 3, Nicotinate-nucleotide adenylyltransferase 3, NaMN adenylyltransferase 3, Pyridine nucleotide adenylyltransferase 3, PNAT-3, NMNAT3
Application Note:
For WB starting dilution is: 1:1000
Background:
The coenzyme NAD and its derivatives are involved in
hundreds of metabolic redox reactions and are utilized in protein
ADP-ribosylation, histone deacetylation, and in some Ca(2+)
signaling pathways. NMNAT (EC 2.7.7.1) is a central enzyme in NAD
biosynthesis, catalyzing the condensation of nicotinamide
mononucleotide (NMN) or nicotinic acid mononucleotide (NaMN) with
the AMP moiety of ATP to form NAD or NaAD (Zhang et al., 2003
[PubMed 12574164]).
Background References:
- Di Stefano, M., et al. Blood Cells Mol. Dis. 45(1):33-39(2010)
- Lau, C., et al. J. Biol. Chem. 285(24):18868-18876(2010)
- Sorci, L., et al. Biochemistry 46(16):4912-4922(2007)
- Berger, F., et al. J. Biol. Chem. 280(43):36334-36341(2005)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This NMNAT3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 150-178 amino acids from the Central region of human NMNAT3.
NCBI Gene ID #:
349565
NCBI Official Name:
Nicotinamide mononucleotide adenylyltransferase 3
NCBI Official Symbol:
NMNAT3
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
28 kDa
Protein Accession #:
Q96T66
Protein GI Number:
116242680
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Obesity,Signal Transduction
Swissprot #:
Q96T66
User NOte:
Optimal dilutions for each application to be determined by the researcher.