TIMM50 Antibody

ProSci
Product Code: PSI-60-301
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-60-301-400ul400ul£626.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Images

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Western blot analysis in MDA-MB453 cell line lysates (35ug/lane).

Western blot analysis in MDA-MB453 cell line lysates (35ug/lane).

Further Information

Additional Names:
Mitochondrial import inner membrane translocase subunit TIM50, TIMM50, TIM50
Application Note:
For WB starting dilution is: 1:1000
Background:
Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane. Has some phosphatase activity in vitro; however such activity may not be relevant in vivo. Isoform 2 may participate in the release of snRNPs and SMN from the Cajal body.
Background References:
  • Ewing, R.M., et al. Mol. Syst. Biol. 3, 89 (2007) :
  • Xu, H., et al. BMC Cell Biol.(1), 29 (2005) :
  • Guo, Y., et al. J. Biol. Chem. 279(23):24813-24825(2004)
  • Yuryev, A., et al. Genomics 81(2):112-125(2003)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This TIMM50 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 74-104 amino acids from the N-terminal region of human TIMM50.
NCBI Gene ID #:
92609
NCBI Official Name:
Mitochondrial import inner membrane translocase subunit TIM50
NCBI Official Symbol:
TIMM50
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
40 kDa
Protein Accession #:
Q3ZCQ8
Protein GI Number:
83305924
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Obesity,Signal Transduction
Swissprot #:
Q3ZCQ8
User NOte:
Optimal dilutions for each application to be determined by the researcher.