SH2B1 Antibody

ProSci
Product Code: PSI-58-193
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-58-193-400ul400ul£626.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Images

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Western blot analysis in 293 cell line lysates (35ug/lane).

Western blot analysis in 293 cell line lysates (35ug/lane).

Further Information

Additional Names:
SH2B adapter protein 1, Pro-rich, PH and SH2 domain-containing signaling mediator, PSM, SH2 domain-containing protein 1B, SH2B1, KIAA1299, SH2B
Application Note:
For WB starting dilution is: 1:1000
Background:
This gene encodes a member of the SH2-domain containing mediators family. The encoded protein mediates activation of various kinases and may function in cytokine and growth factor receptor signaling and cellular transformation. Alternatively spliced transcript variants have been described. [provided by RefSeq].
Background References:
  • Fontaine-Bisson, B., et al. Diabetologia 53(10):2155-2162(2010)
  • Holzapfel, C., et al. IntObes (Lond) 34(10):1538-1545(2010)
  • Shi, J., et al. Am. J. Epidemiol. 172(3):244-254(2010)
  • Haupt, A., et al. Obesity (Silver Spring) 18(6):1212-1217(2010)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Predicted species reactivity based on immunogen sequence: Mouse, Rat
Immunogen:
This SH2B1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 725-752 amino acids from the C-terminal region of human SH2B1.
NCBI Gene ID #:
25970
NCBI Official Name:
SH2B adapter protein 1
NCBI Official Symbol:
SH2B1
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
79 kDa
Protein Accession #:
Q9NRF2
Protein GI Number:
313104186
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Obesity,Signal Transduction
Swissprot #:
Q9NRF2
User NOte:
Optimal dilutions for each application to be determined by the researcher.