MMACHC Antibody
| Code | Size | Price |
|---|
| PSI-60-875-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
Methylmalonic aciduria and homocystinuria type C protein, MMACHC
Application Note:
For WB starting dilution is: 1:1000
Background:
The exact function of the protein encoded by this gene is
not known, however, its C-terminal region shows similarity to TonB,
a bacterial protein involved in energy transduction for cobalamin
(vitamin B12) uptake. Hence, it is postulated that this protein may
have a role in the binding and intracellular trafficking of
cobalamin. Mutations in this gene are associated with methylmalonic
aciduria and homocystinuria type cblC.
Background References:
- Froese, D.S., et al. Mol. Genet. Metab. 100(1):29-36(2010)
- Davila, S., et al. Genes Immun. 11(3):232-238(2010)
- Profitlich, L.E., et al. Mol. Genet. Metab. 98(4):344-348(2009)
- Kim, J., et al. J. Biol. Chem. 284(48):33418-33424(2009)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This MMACHC antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 239-267 amino acids from the C-terminal region of human MMACHC.
NCBI Gene ID #:
25974
NCBI Official Name:
Methylmalonic aciduria and homocystinuria type C protein
NCBI Official Symbol:
MMACHC
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
32 kDa
Protein Accession #:
Q9Y4U1
Protein GI Number:
85681045
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Obesity,Signal Transduction
Swissprot #:
Q9Y4U1
User NOte:
Optimal dilutions for each application to be determined by the researcher.