MKL1 Antibody
| Code | Size | Price |
|---|
| PSI-60-159-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
MKL/myocardin-like protein 1, Megakaryoblastic leukemia 1 protein, Megakaryocytic acute leukemia protein, Myocardin-related transcription factor A, MRTF-A, MKL1, KIAA1438, MAL
Application Note:
For WB starting dilution is: 1:1000
Background:
The protein encoded by this gene interacts with the
transcription factor myocardin, a key regulator of smooth muscle
cell differentiation. The encoded protein is predominantly nuclear
and may help transduce signals from the cytoskeleton to the
nucleus. This gene is involved in a specific translocation event
that creates a fusion of this gene and the RNA-binding motif
protein-15 gene. This translocation has been associated with acute
megakaryocytic leukemia.
Background References:
- Gilles, L., et al. Blood 114(19):4221-4232(2009)
- Hinohara, K., et al. Hum. Genet. 126(4):539-547(2009)
- Estrada, K., et al. Hum. Mol. Genet. 18(18):3516-3524(2009)
- Brandt, D.T., et al. Nat. Cell Biol. 11(5):557-568(2009)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This MKL1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 497-525 amino acids from the Central region of human MKL1.
NCBI Gene ID #:
57591
NCBI Official Name:
MKL/myocardin-like protein 1
NCBI Official Symbol:
MKL1
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
99 kDa
Protein Accession #:
Q969V6
Protein GI Number:
32363202
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Obesity,Signal Transduction
Swissprot #:
Q969V6
User NOte:
Optimal dilutions for each application to be determined by the researcher.