DHODH Antibody
| Code | Size | Price |
|---|
| PSI-60-535-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
Dihydroorotate dehydrogenase (quinone), mitochondrial, DHOdehase, Dihydroorotate oxidase, DHODH
Application Note:
For WB starting dilution is: 1:1000
Background:
The protein encoded by this gene catalyzes the fourth
enzymatic step, the ubiquinone-mediated oxidation of dihydroorotate
to orotate, in de novo pyrimidine biosynthesis. This protein is a
mitochondrial protein located on the outer surface of the inner
mitochondrial membrane.
Background References:
- Hail, N. Jr., et al. Free Radic. Biol. Med. 49(1):109-116(2010)
- Ng, S.B., et al. Nat. Genet. 42(1):30-35(2010)
- Grabar, P.B., et al. Ann. Rheum. Dis. 68(8):1367-1368(2009)
- Pawlik, A., et al. Pharmacogenomics 10(2):303-309(2009)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This DHODH antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 166-194 amino acids from the Central region of human DHODH.
NCBI Gene ID #:
1723
NCBI Official Name:
Dihydroorotate dehydrogenase (quinone), mitochondrial
NCBI Official Symbol:
DHODH
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
43 kDa
Protein Accession #:
Q02127
Protein GI Number:
56405372
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Obesity,Signal Transduction
Swissprot #:
Q02127
User NOte:
Optimal dilutions for each application to be determined by the researcher.