AADAT Antibody
| Code | Size | Price |
|---|
| PSI-55-064-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial, KAT/AadAT, 2-aminoadipate aminotransferase, 2-aminoadipate transaminase, Alpha-aminoadipate aminotransferase, AadAT, Kynurenine aminotransferase II, Kynurenine--oxoglutarate aminotransferase II, Kynurenine--oxoglutarate transaminase 2, Kynurenine--oxoglutarate transaminase II, AADAT, KAT2
Application Note:
For WB starting dilution is: 1:1000
Background:
This gene encodes a protein that is highly similar to
mouse and rat kynurenine aminotransferase II. The rat protein is a
homodimer with two transaminase activities. One activity is the
transamination of alpha-aminoadipic acid, a final step in the
saccaropine pathway which is the major pathway for L-lysine
catabolism. The other activity involves the transamination of
kynurenine to produce kynurenine acid, the precursor of kynurenic
acid which has neuroprotective properties. Two alternative
transcripts encoding the same isoform have been identified,
however, additional alternative transcripts and isoforms may exist.
Background References:
- Han, Q., et al. Biosci. Rep. 28(4):205-215(2008)
- Rossi, F., et al. J. Biol. Chem. 283(6):3559-3566(2008)
- Han, Q., et al. J. Biol. Chem. 283(6):3567-3573(2008)
- Lamesch, P., et al. Genomics 89(3):307-315(2007)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This AADAT antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 196-224 amino acids from the Central region of human AADAT.
NCBI Gene ID #:
51166
NCBI Official Name:
Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial
NCBI Official Symbol:
AADAT
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
47 kDa
Protein Accession #:
Q8N5Z0
Protein GI Number:
46395904
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Obesity,Signal Transduction
Swissprot #:
Q8N5Z0
User NOte:
Optimal dilutions for each application to be determined by the researcher.