KLB Antibody
| Code | Size | Price |
|---|
| PSI-61-275-200ul | 200ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
Beta-klotho, BKL, BetaKlotho, Klotho beta-like protein, KLB
Application Note:
For WB starting dilution is: 1:2000
Background:
Contributes to the transcriptional repression of cholesterol 7-alpha-hydroxylase (CYP7A1), the rate-limiting enzyme in bile acid synthesis. Probably inactive as a glycosidase. Increases the ability of FGFR1 and FGFR4 to bind FGF21 (By similarity).
Background References:
- Hayashi A.,et al.Submitted (FEB-2002) to the EMBL/GenBank/DDBJ databases.
- Wu X.,et al.J. Biol. Chem. 283:33304-33309(2008).
- Micanovic R.,et al.J. Cell. Physiol. 219:227-234(2009).
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This KLB antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 1-29 amino acids from human KLB.
NCBI Gene ID #:
152831
NCBI Official Name:
Beta-klotho
NCBI Official Symbol:
KLB
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
120 kDa
Protein Accession #:
Q86Z14
Protein GI Number:
74750586
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Obesity,Signal Transduction
Swissprot #:
Q86Z14
User NOte:
Optimal dilutions for each application to be determined by the researcher.