UGT2B7 Antibody
| Code | Size | Price |
|---|
| PSI-59-716-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
UDP-glucuronosyltransferase 2B7, UDPGT 2B7,4-catechol estrogen-specific UDPGT, UDP-glucuronosyltransferase 2B9, UDPGT 2B9, UDPGTh-2, UGT2B7, UGTB2B9
Application Note:
For WB starting dilution is: 1:1000
Background:
The UGTs (EC 2.4.1.17) serve a major role in the
conjugation and subsequent elimination of potentially toxic
xenobiotics and endogenous compounds. UGT2B7 has unique specificity
for 3,4-catechol estrogens and estriol, suggesting that it may play
an important role in regulating the level and activity of these
potent estrogen metabolites. Its subcellular location is the
microsome.
Background References:
- Joy, M.S., et al. Eur. J. Clin. Pharmacol. 66(11):1119-1130(2010)
- Canzian, F., et al. Hum. Mol. Genet. 19(19):3873-3884(2010)
- Hu, M., et al. Pharmacogenet. Genomics 20(10):634-637(2010)
- Woillard, J.B., et al. BrClin Pharmacol 69(6):675-683(2010)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This UGT2B7 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 97-126 amino acids from the N-terminal region of human UGT2B7.
NCBI Gene ID #:
7364
NCBI Official Name:
UDP-glucuronosyltransferase 2B7
NCBI Official Symbol:
UGT2B7
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
61 kDa
Protein Accession #:
P16662
Protein GI Number:
136727
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Obesity,Signal Transduction
Swissprot #:
P16662
User NOte:
Optimal dilutions for each application to be determined by the researcher.