GNMT Antibody
Code | Size | Price |
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PSI-59-615-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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Further Information
Additional Names:
Glycine N-methyltransferase, GNMT
Application Note:
For WB starting dilution is: 1:1000
Background:
The protein encoded by this gene is an enzyme that
catalyzes the conversion of S-adenosyl-L-methionine (along with
glycine) to S-adenosyl-L-homocysteine and sarcosine. The encoded
protein is found in the cytoplasm and acts as a homotetramer.
Defects in this gene are a cause of GNMT deficiency
(hypermethioninemia).
Background References:
- Jugessur, A., et al. PLoS ONE(7), E11493 (2010) :
- Lee, C.M., et al. Gene 443 (1-2), 151-157 (2009) :
- Boyles, A.L., et al. Genet. Epidemiol. 33(3):247-255(2009)
- Yen, C.H., et al. Toxicol. Appl. Pharmacol. 235(3):296-304(2009)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Predicted species reactivity based on immunogen sequence: Pig, Rabbit
Immunogen:
This GNMT antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 78-106 amino acids from the Central region of human GNMT.
NCBI Gene ID #:
27232
NCBI Official Name:
Glycine N-methyltransferase
NCBI Official Symbol:
GNMT
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
33 kDa
Protein Accession #:
Q14749
Protein GI Number:
12644416
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Obesity,Signal Transduction
Swissprot #:
Q14749
User NOte:
Optimal dilutions for each application to be determined by the researcher.