GNPTG Antibody
| Code | Size | Price |
|---|
| PSI-59-732-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
N-acetylglucosamine-1-phosphotransferase subunit gamma, GlcNAc-1-phosphotransferase subunit gamma, UDP-N-acetylglucosamine-1-phosphotransferase subunit gamma, GNPTG, C16orf27, GNPTAG
Application Note:
For WB starting dilution is: 1:1000
Background:
This gene encodes the gamma sunbunit of the
N-acetylglucosamine-1-phosphotransferase complex. This hexameric
complex, composed of alpha, beta and gamma subunits, catalyzes the
first step in synthesis of a mannose 6-phosphate lysosomal
recognition marker. This enzyme complex is necessary for targeting
of lysosomal hydrolases to the lysosome. Mutations in the gene
encoding the gamma subunit have been associated with mucolipidosis
IIIC, also known as mucolipidosis III gamma.
Background References:
- Kang, C., et al. N. Engl. J. Med. 362(8):677-685(2010)
- Qian, Y., et al. J. Biol. Chem. 285(5):3360-3370(2010)
- Pohl, S., et al. Am. J. Med. Genet.152A (1), 124-132 (2010) :
- Encarnacao, M., et al. Clin. Genet. 76(1):76-84(2009)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This GNPTG antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 266-296 amino acids from the C-terminal region of human GNPTG.
NCBI Gene ID #:
84572
NCBI Official Name:
N-acetylglucosamine-1-phosphotransferase subunit gamma
NCBI Official Symbol:
GNPTG
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
34 kDa
Protein Accession #:
Q9UJJ9
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Obesity,Signal Transduction
Swissprot #:
Q9UJJ9
User NOte:
Optimal dilutions for each application to be determined by the researcher.