DAO Antibody
| Code | Size | Price |
|---|
| PSI-57-366-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
D-amino-acid oxidase, DAAO, DAMOX, DAO, DAO, DAMOX
Application Note:
For WB starting dilution is: 1:1000
Background:
This gene encodes the peroxisomal enzyme D-amino acid
oxidase. The enzyme is a flavoprotein which uses flavin adenine
dinucleotide (FAD) as its prosthetic group. Its substrates include
a wide variety of D-amino acids, but it is inactive on the
naturally occurring L-amino acids. Its biological function is not
known; it may act as a detoxifying agent which removes D-amino
acids that accumulate during aging. In mice, it degrades D-serine,
a co-agonist of the NMDA receptor. This gene may play a role in the
pathophysiology of schizophrenia.
Background References:
- Kim, B., et al. Psychiatry Res 179(2):121-125(2010)
- Caldinelli, L., et al. Protein Sci. 19(8):1500-1512(2010)
- Ruano, G., et al. Pharmacogenomics 11(7):959-971(2010)
- Ohnuma, T., et al. Schizophr. Res. 118 (1-3), 300-302 (2010) :
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This DAO antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 259-287 amino acids from the Central region of human DAO.
NCBI Gene ID #:
1610
NCBI Official Name:
D-amino-acid oxidase
NCBI Official Symbol:
DAO
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
39 kDa
Protein Accession #:
P14920
Protein GI Number:
25453448
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Obesity,Signal Transduction
Swissprot #:
P14920
User NOte:
Optimal dilutions for each application to be determined by the researcher.