AKR7A3 Antibody

ProSci
Product Code: PSI-61-220
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-61-220-200ul200ul£626.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Images

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Western Blot at 1:2000 dilution Lane 1: 293T/17 whole cell lysate Lane 2: human liver lysate Lane 3: HepG2 whole cell lysate Lane 4: SK-BR-3 whole cell lysate Lysates/proteins at 20 ug per lane.

Western Blot at 1:2000 dilution Lane 1: 293T/17 whole cell lysate Lane 2: human liver lysate Lane 3: HepG2 whole cell lysate Lane 4: SK-BR-3 whole cell lysate Lysates/proteins at 20 ug per lane.

Further Information

Additional Names:
Aflatoxin B1 aldehyde reductase member 3, 1.-.-.-, AFB1 aldehyde reductase 2, AFB1-AR 2, AKR7A3, AFAR2
Application Note:
For WB starting dilution is: 1:2000
Background:
Can reduce the dialdehyde protein-binding form of aflatoxin B1 (AFB1) to the non-binding AFB1 dialcohol. May be involved in protection of liver against the toxic and carcinogenic effects of AFB1, a potent hepatocarcinogen.
Background References:
  • Knight L.P.,et al.Carcinogenesis 20:1215-1223(1999).
  • Praml C.,et al.Oncogene 22:4765-4773(2003).
  • Gregory S.G.,et al.Nature 441:315-321(2006).
  • Bodreddigari S.,et al.Chem. Res. Toxicol. 21:1134-1142(2008).
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This AKR7A3 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 33-64 amino acids from the human region of human AKR7A3.
NCBI Gene ID #:
22977
NCBI Official Name:
Aflatoxin B1 aldehyde reductase member 3
NCBI Official Symbol:
AKR7A3
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
37 kDa
Protein Accession #:
O95154
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Obesity,Signal Transduction
Swissprot #:
O95154
User NOte:
Optimal dilutions for each application to be determined by the researcher.