GATM Antibody
| Code | Size | Price |
|---|
| PSI-60-678-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
Glycine amidinotransferase, mitochondrial, L-arginine:glycine amidinotransferase, Transamidinase, GATM, AGAT
Application Note:
For WB starting dilution is: 1:1000
Background:
This gene encodes a mitochondrial enzyme that belongs to
the amidinotransferase family. This enzyme is involved in creatine
biosynthesis, whereby it catalyzes the transfer of a guanido group
from L-arginine to glycine, resulting in guanidinoacetic acid, the
immediate precursor of creatine. Mutations in this gene cause
arginine:glycine amidinotransferase deficiency, an inborn error of
creatine synthesis characterized by mental retardation, language
impairment, and behavioral disorders.
Background References:
- Kottgen, A., et al. Nat. Genet. 42(5):376-384(2010)
- Kottgen, A., et al. Nat. Genet. 41(6):712-717(2009)
- Lion-Francois, L., et al. Neurology 67(9):1713-1714(2006)
- Cullen, M.E., et al. Circulation 114 (1 SUPPL), I16-I20 (2006) :
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Predicted species reactivity based on immunogen sequence: Bovine, Monkey, Mouse, Pig, Rat
Immunogen:
This GATM antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 350-378 amino acids from the C-terminal region of human GATM.
NCBI Gene ID #:
2628
NCBI Official Name:
Glycine amidinotransferase, mitochondrial
NCBI Official Symbol:
GATM
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
48 kDa
Protein Accession #:
P50440
Protein GI Number:
1730201
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Obesity,Signal Transduction
Swissprot #:
P50440
User NOte:
Optimal dilutions for each application to be determined by the researcher.