PRRG1 Antibody
| Code | Size | Price |
|---|
| PSI-57-002-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
Transmembrane gamma-carboxyglutamic acid protein 1, Proline-rich gamma-carboxyglutamic acid protein 1, Proline-rich Gla protein 1, PRRG1, PRGP1, TMG1
Application Note:
For WB starting dilution is: 1:1000
Background:
This gene encodes a vitamin K-dependent,
gamma-carboxyglutamic acid (Gla)-containing, single-pass
transmembrane protein. This protein contains a Gla domain at the
N-terminus, preceded by a propeptide sequence required for
post-translational gamma-carboxylation of specific glutamic acid
residues by a vitamin K-dependent gamma-carboxylase. The C-terminus
is proline-rich containing PPXY and PXXP motifs found in a variety
of signaling and cytoskeletal proteins. This gene is highly
expressed in the spinal cord. Several alternatively spliced
transcript variants have been found for this gene. [provided by
RefSeq].
Background References:
- Lamesch, P., et al. Genomics 89(3):307-315(2007)
- Wang, A.G., et al. Biochem. Biophys. Res. Commun. 345(3):1022-1032(2006)
- Ross, M.T., et al. Nature 434(7031):325-337(2005)
- Kulman, J.D., et al. Proc. Natl. Acad. Sci. U.S.A. 94(17):9058-9062(1997)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Predicted species reactivity based on immunogen sequence: Bovine
Immunogen:
This PRRG1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 30-59 amino acids from the N-terminal region of human PRRG1.
NCBI Gene ID #:
5638
NCBI Official Name:
Transmembrane gamma-carboxyglutamic acid protein 1
NCBI Official Symbol:
PRRG1
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
25 kDa
Protein Accession #:
O14668
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Obesity,Signal Transduction
Swissprot #:
O14668
User NOte:
Optimal dilutions for each application to be determined by the researcher.