BCMO1 Antibody

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ProSci
Product Code: PSI-55-200
Product Group: Primary Antibodies
Supplier: ProSci
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PSI-55-200-400ul400ul£626.00
Quantity:
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Overview

Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Images

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Western blot analysis in WiDr cell line lysates (35ug/lane).
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Western blot analysis in WiDr cell line lysates (35ug/lane).

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Further Information

Additional Names:
Beta,beta-carotene 15,15'-monooxygenase, Beta-carotene dioxygenase 1, Beta-carotene oxygenase 1 {ECO:0000312|HGNC:HGNC:13815}, BCO1 (HGNC:13815)
Application Note:
For WB starting dilution is: 1:1000
Background:
Vitamin A metabolism is important for vital processes such as vision, embryonic development, cell differentiation, and membrane and skin protection. The protein encoded by this gene is a key enzyme in beta-carotene metabolism to vitamin A. It catalyzes the oxidative cleavage of beta,beta-carotene into two retinal molecules.
Background References:
  • Lietz, G., et al. Arch. Biochem. Biophys. 502(1):8-16(2010)
  • Kim, Y.S., et al. Biotechnol. Lett. 32(6):847-853(2010)
  • Dastani, Z., et al. Eur. J. Hum. Genet. 18(3):342-347(2010)
  • Perry, J.R., et al. Diabetologia 52(10):2117-2121(2009)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This BCMO1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 263-292 amino acids from the Central region of human BCMO1.
NCBI Gene ID #:
53630
NCBI Official Name:
Beta,beta-carotene 15,15'-monooxygenase
NCBI Official Symbol:
BCO1
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
63 kDa
Protein Accession #:
Q9HAY6
Protein GI Number:
41688803
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Obesity,Signal Transduction
Swissprot #:
Q9HAY6
User NOte:
Optimal dilutions for each application to be determined by the researcher.