TMLHE Antibody
| Code | Size | Price |
|---|
| PSI-55-385-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
Trimethyllysine dioxygenase, mitochondrial, Epsilon-trimethyllysine 2-oxoglutarate dioxygenase, Epsilon-trimethyllysine hydroxylase, TML hydroxylase, TML-alpha-ketoglutarate dioxygenase, TML dioxygenase, TMLD, TMLHE, TMLH
Application Note:
For WB starting dilution is: 1:1000
Background:
This gene encodes the protein trimethyllysine dioxygenase
which is the first enzyme in the carnitine biosynthesis pathway.
Carnitine play an essential role in the transport of activated
fatty acids across the inner mitochondrial membrane. The encoded
protein converts trimethyllysine into hydroxytrimethyllysine. A
pseudogene of this gene is found on chromosome X. Alternate
splicing results in multiple transcript variants.
Background References:
- Monfregola, J., et al. Gene 395 (1-2), 86-97 (2007) :
- Monfregola, J., et al. J. Cell. Physiol. 204(3):839-847(2005)
- Vaz, F.M., et al. J. Biol. Chem. 276(36):33512-33517(2001)
- Rogner, U.C., et al. Genome Res. 6(10):922-934(1996)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Predicted species reactivity based on immunogen sequence: Bovine, Mouse
Immunogen:
This TMLHE antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 120-149 amino acids from the N-terminal region of human TMLHE.
NCBI Gene ID #:
55217
NCBI Official Name:
Trimethyllysine dioxygenase, mitochondrial
NCBI Official Symbol:
TMLHE
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
50 kDa
Protein Accession #:
Q9NVH6
Protein GI Number:
21542295
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Obesity,Signal Transduction
Swissprot #:
Q9NVH6
User NOte:
Optimal dilutions for each application to be determined by the researcher.