PPP1R3B Antibody
Code | Size | Price |
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PSI-59-734-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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Further Information
Additional Names:
Protein phosphatase 1 regulatory subunit 3B, Hepatic glycogen-targeting protein phosphatase 1 regulatory subunit GL, Protein phosphatase 1 regulatory subunit 4, PP1 subunit R4, Protein phosphatase 1 subunit GL, PTG, PPP1R3B, PPP1R4
Application Note:
For WB starting dilution is: 1:1000
Background:
The protein phosphatase-1 (PP1) catalytic subunit (PPP1CA;
MIM 176875) is regulated by targeting subunits, such as PP1R3B.
PP1R3B suppresses the rate at which PP1 dephosphorylates (i.e.,
inactivates) glycogen phosphorylase (see PYGL; MIM 232700) and
enhances the rate at which it activates glycogen synthase (see
GYS2; MIM 138571) (Doherty et al., 1995 [PubMed 7498521]).[supplied
by OMIM].
Background References:
- Montori-Grau, M., et al. Biochem. J. 405(1):107-113(2007)
- Lamesch, P., et al. Genomics 89(3):307-315(2007)
- Ceulemans, H., et al. Bioessays 24(4):371-381(2002)
- Doherty, M.J., et al. FEBS Lett. 375(3):294-298(1995)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This PPP1R3B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 205-231 amino acids from the C-terminal region of human PPP1R3B.
NCBI Gene ID #:
79660
NCBI Official Name:
Protein phosphatase 1 regulatory subunit 3B
NCBI Official Symbol:
PPP1R3B
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
33 kDa
Protein Accession #:
Q86XI6
Protein GI Number:
74727837
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Obesity,Signal Transduction
Swissprot #:
Q86XI6
User NOte:
Optimal dilutions for each application to be determined by the researcher.