NFS1 Antibody
Code | Size | Price |
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PSI-58-465-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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Further Information
Additional Names:
Cysteine desulfurase, mitochondrial, NFS1, NIFS
Application Note:
For WB starting dilution is: 1:1000
Background:
Iron-sulfur clusters are required for the function of many
cellular enzymes. The proteins encoded by this gene supply
inorganic sulfur to these clusters by removing the sulfur from
cysteine, creating alanine in the process. This gene uses alternate
in-frame translation initiation sites to generate mitochondrial
forms and cytoplasmic/nuclear forms. Selection of the alternative
initiation sites is determined by the cytosolic pH. The encoded
proteins belong to the class-V family of pyridoxal
phosphate-dependent aminotransferases. Alternatively spliced
transcript variants have been described.
Background References:
- Naamati, A., et al. J. Biol. Chem. 284(44):30200-30208(2009)
- Marelja, Z., et al. J. Biol. Chem. 283(37):25178-25185(2008)
- Wu, C., et al. Proteomics 7(11):1775-1785(2007)
- Lamesch, P., et al. Genomics 89(3):307-315(2007)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Predicted species reactivity based on immunogen sequence: Mouse, Rat
Immunogen:
This NFS1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 121-149 amino acids from the Central region of human NFS1.
NCBI Gene ID #:
9054
NCBI Official Name:
Cysteine desulfurase, mitochondrial
NCBI Official Symbol:
NFS1
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
50 kDa
Protein Accession #:
Q9Y697
Protein GI Number:
62512153
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Obesity,Signal Transduction
Swissprot #:
Q9Y697
User NOte:
Optimal dilutions for each application to be determined by the researcher.