PPT1 Antibody
| Code | Size | Price |
|---|
| PSI-58-985-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
Palmitoyl-protein thioesterase 1, PPT-1, Palmitoyl-protein hydrolase 1, PPT1, PPT
Application Note:
For WB starting dilution is: 1:1000
Background:
The protein encoded by this gene is a small glycoprotein
involved in the catabolism of lipid-modified proteins during
lysosomal degradation. The encoded enzyme removes thioester-linked
fatty acyl groups such as palmitate from cysteine residues. Defects
in this gene are a cause of infantile neuronal ceroid
lipofuscinosis 1 (CLN1, or INCL) and neuronal ceroid lipofuscinosis
4 (CLN4). Two transcript variants encoding different isoforms have
been found for this gene.
Background References:
- Ohno, K., et al. Brain Dev. 32(7):524-530(2010)
- Simonati, A., et al. Pediatr. Neurol. 40(4):271-276(2009)
- Martins-de-Souza, D., et al. Eur Arch Psychiatry Clin Neurosci 259(3):151-163(2009)
- Kousi, M., et al. Brain 132 (PT 3), 810-819 (2009) :
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Predicted species reactivity based on immunogen sequence: Monkey
Immunogen:
This PPT1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 189-217 amino acids from the Central region of human PPT1.
NCBI Gene ID #:
5538
NCBI Official Name:
Palmitoyl-protein thioesterase 1
NCBI Official Symbol:
PPT1
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
34 kDa
Protein Accession #:
P50897
Protein GI Number:
1709747
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Obesity,Signal Transduction
Swissprot #:
P50897
User NOte:
Optimal dilutions for each application to be determined by the researcher.