ECH1 Antibody
| Code | Size | Price |
|---|
| PSI-59-987-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
Delta(3,5)-Delta(2,4)-dienoyl-CoA isomerase, mitochondrial, 533-, ECH1
Application Note:
For WB starting dilution is: 1:1000
Background:
This gene encodes a member of the hydratase/isomerase
superfamily. The gene product shows high sequence similarity to
enoyl-coenzyme A (CoA) hydratases of several species, particularly
within a conserved domain characteristic of these proteins. The
encoded protein, which contains a C-terminal peroxisomal targeting
sequence, localizes to the peroxisome. The rat ortholog, which
localizes to the matrix of both the peroxisome and mitochondria,
can isomerize 3-trans,5-cis-dienoyl-CoA to
2-trans,4-trans-dienoyl-CoA, indicating that it is a
delta3,5-delta2,4-dienoyl-CoA isomerase. This enzyme functions in
the auxiliary step of the fatty acid beta-oxidation pathway.
Expression of the rat gene is induced by peroxisome proliferators.
Background References:
- Olsen, J.V., et al. Cell 127(3):635-648(2006)
- Olsen, J.V., et al. Cell 127(3):635-648(2006)
- Kovalyov, L.I., et al. Biochemistry Mosc. 71(4):448-453(2006)
- Goehler, H., et al. Mol. Cell 15(6):853-865(2004)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This ECH1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 223-250 amino acids from the C-terminal region of human ECH1.
NCBI Gene ID #:
1891
NCBI Official Name:
Delta(3,5)-Delta(2,4)-dienoyl-CoA isomerase, mitochondrial
NCBI Official Symbol:
ECH1
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
36 kDa
Protein Accession #:
Q13011
Protein GI Number:
82654933
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Obesity,Signal Transduction
Swissprot #:
Q13011
User NOte:
Optimal dilutions for each application to be determined by the researcher.