MOCS2 Antibody

ProSci
Product Code: PSI-58-378
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-58-378-400ul400ul£626.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Images

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Western blot analysis in NCI-H460 cell line lysates (35ug/lane).

Western blot analysis in NCI-H460 cell line lysates (35ug/lane).

Further Information

Additional Names:
Molybdopterin synthase catalytic subunit {ECO:0000255|HAMAP-Rule:MF_03052}, 28112 {ECO:0000255|HAMAP-Rule:MF_03052}, MOCO1-B, Molybdenum cofactor synthesis protein 2 large subunit {ECO:0000255|HAMAP-Rule:MF_03052}, Molybdenum cofactor synthesis protein 2B {ECO:0000255|HAMAP-Rule:MF_03052}, MOCS2B {ECO:0000255|HAMAP-Rule:MF_03052}, Molybdopterin-synthase large subunit, MPT synthase large subunit, MOCS2 {ECO:0000255|HAMAP-Rule:MF_03052}, MCBPE, MOCO1
Application Note:
For WB starting dilution is: 1:1000
Background:
Eukaryotic molybdoenzymes use a unique molybdenum cofactor (MoCo) consisting of a pterin, termed molybdopterin, and the catalytically active metal molybdenum. MoCo is synthesized from precursor Z by the heterodimeric enzyme molybdopterin synthase. The large and small subunits of molybdopterin synthase are both encoded from this gene by overlapping open reading frames. The proteins were initially thought to be encoded from a bicistronic transcript. They are now thought to be encoded from monocistronic transcripts. Alternatively spliced transcripts have been found for this locus that encode the large and small subunits.
Background References:
  • Per, H., et al. Brain Dev. 29(6):365-368(2007)
  • Hahnewald, R., et al. Mol. Genet. Metab. 89(3):210-213(2006)
  • Beausoleil, S.A., et al. Nat. Biotechnol. 24(10):1285-1292(2006)
  • Leimkuhler, S., et al. Hum. Genet. 117(6):565-570(2005)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This MOCS2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 14-43 amino acids from the N-terminal region of human MOCS2.
NCBI Gene ID #:
4338
NCBI Official Name:
Molybdopterin synthase catalytic subunit {ECO:0000255|HAMAP-Rule:MF_03052}
NCBI Official Symbol:
MOCS2
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
21 kDa
Protein Accession #:
O96007
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Obesity,Signal Transduction
Swissprot #:
O96007
User NOte:
Optimal dilutions for each application to be determined by the researcher.